SCHEMBL30375220

SCHEMBL30375220

Cc1cc(Cc2cccc(O)c2C)c(O)c(Cc2cc(C)cc(Cc3cccc(O)c3C)c2O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.59
CYP2C9 P11712 3/20 0.49
CYP2C19 P33261 3/20 0.49
HIF1A Q16665 3/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSPA5 P11021 2/20 0.46
GABRA1 P14867 2/20 0.42
GABRB2 P47870 2/20 0.42
TRPA1 O75762 2/20 0.42
ATM Q13315 1/20 0.42
CYP2D6 P10635 1/20 0.40
HSD17B10 Q99714 1/20 0.40
IDH1 O75874 1/20 0.40
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
HSP90AA1 P07900 1/20 0.39
CNR2 P34972 1/20 0.38
GAA P10253 1/20 0.37
SELL P14151 1/20 0.37
SELP P16109 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29290540 1.00 AMY1A (0.59) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL28694834 0.91 AMY1A (0.50) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL845508 0.86 HSPA5 (0.56) HIF1AHSPA5GABRA1GABRB2TRPA1
SCHEMBL3694841 0.86 HSPA5 (0.71) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29290539 0.85 AMY1A (0.69) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30375225 0.85 AMY1A (0.69) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL7758427 0.85 AMY1A (0.69) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29102692 0.84 AMY1A (0.62) AMY1AHIF1ASMN1; SMN2HSPA5TRPA1
SCHEMBL29643285 0.81 AMY1A (0.58) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL21232598 0.80 AMY1A (0.54) AMY1ACYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed