SCHEMBL30375239

SCHEMBL30375239

Cc1cc(Cc2ccc(O)c(F)c2)cc(Cc2ccc(O)c(F)c2)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
SHBG P04278 1/20 0.53
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
MAPT P10636 1/20 0.42
CYP3A4 P08684 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP17A1 P05093 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22500136 1.00 ESR1 (0.53) ESR1ESR2SHBGPTGS1PTGS2
SCHEMBL3187895 0.87 ESR1 (0.71) ESR1ESR2SHBGPTGS1PTGS2
SCHEMBL4055517 0.87 ESR1 (0.71) ESR1ESR2SHBGPTGS1PTGS2
SCHEMBL4063169 0.87 ESR1 (0.71) ESR1ESR2SHBGPTGS1PTGS2
SCHEMBL29636483 0.87 ESR1 (0.71) ESR1ESR2SHBGPTGS1PTGS2
SCHEMBL8351876 0.85 ESR1 (0.69) ESR1ESR2SHBGPTGS1PTGS2
SCHEMBL3194268 0.85 CA1 (0.59) ESR1ESR2SHBGPTGS2MAPT
SCHEMBL6846484 0.82 ESR1 (0.74) ESR1ESR2SHBGMAPTCYP3A4
SCHEMBL30783352 0.82 ESR1 (0.74) ESR1ESR2SHBGMAPTCYP3A4
SCHEMBL4066304 0.82 ESR1 (0.74) ESR1ESR2SHBGMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed