Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456505 | 1.00 | ESR1 (0.56) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL13609112 | 0.98 | ESR1 (0.59) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL218341 | 0.84 | ESR1 (0.54) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL19038984 | 0.84 | ESR1 (0.54) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL28680998 | 0.84 | ESR1 (0.48) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL19039034 | 0.83 | ESR1 (0.52) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL17354943 | 0.83 | ESR1 (0.52) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL8066762 | 0.83 | ESR1 (0.52) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL4064068 | 0.82 | ESR1 (0.46) | ESR1ESR2KEAP1MEN1MAPT | |
| SCHEMBL13609021 | 0.82 | ESR1 (0.46) | ESR1ESR2KEAP1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| CN-113785023-B | Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same | 株式会社百乐 | 2023-05-12 | — | — | CN | disclosed |