Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112432 | 1.00 | TSHR (0.65) | TSHRALDH1A1MAPTSRD5A2TTR | |
| SCHEMBL2964948 | 0.83 | TSHR (0.43) | TSHRALDH1A1MAPTSRD5A2KDM4E | |
| SCHEMBL177140 | 0.83 | TSHR (0.65) | TSHRALDH1A1MAPTSRD5A2TTR | |
| SCHEMBL393467 | 0.81 | PARP1 (0.48) | TSHRMAPTCA2SMN1; SMN2 | |
| SCHEMBL1841487 | 0.81 | MAPT (0.51) | TSHRALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30375381 | 0.80 | CYP1A2 (0.58) | ALDH1A1MAPTSRD5A2ALOX15L3MBTL1 | |
| SCHEMBL26092638 | 0.80 | CYP1A2 (0.58) | ALDH1A1MAPTSRD5A2ALOX15L3MBTL1 | |
| SCHEMBL588825 | 0.79 | TTR (0.56) | TSHRALDH1A1MAPTSRD5A2TTR | |
| SCHEMBL8352471 | 0.79 | TSHR (1.00) | TSHRALDH1A1MAPTSRD5A2TTR | |
| SCHEMBL371998 | 0.79 | TSHR (1.00) | TSHRALDH1A1MAPTSRD5A2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4426700-A1 | HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS | Merck Patent GmbH (DE) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023078813-A1 | HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |