SCHEMBL30375381

SCHEMBL30375381

O=C(c1ccccc1)c1ccc(Cl)c(Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
HPGD P15428 1/20 0.58
CYP2C19 P33261 1/20 0.58
VCAM1 P19320 2/20 0.57
ATM Q13315 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
SRD5A2 P31213 2/20 0.55
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 2/20 0.47
RAB9A P51151 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.47
PBRM1 Q86U86 1/20 0.47
ALOX15 P16050 2/20 0.47
CNR2 P34972 2/20 0.46
HTT P42858 1/20 0.46
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26092638 1.00 CYP1A2 (0.58) CYP1A2CYP2D6HPGDCYP2C19VCAM1
SCHEMBL1129174 0.85 L3MBTL1 (0.55) CYP1A2CYP2D6HPGDCYP2C19VCAM1
SCHEMBL30391232 0.82 HPGD (0.64) CYP1A2CYP2D6HPGDCYP2C19ATM
SCHEMBL27563858 0.82 HPGD (0.64) CYP1A2CYP2D6HPGDCYP2C19ATM
SCHEMBL333237 0.82 SRD5A2 (0.78) VCAM1ATMTDP1L3MBTL1SRD5A2
SCHEMBL30375607 0.80 TSHR (0.65) TDP1L3MBTL1SRD5A2ALDH1A1KMT2A
SCHEMBL112432 0.80 TSHR (0.65) TDP1L3MBTL1SRD5A2ALDH1A1KMT2A
SCHEMBL31255379 0.80 ALDH1A1 (0.50) CYP1A2CYP2D6HPGDCYP2C19VCAM1
SCHEMBL28635108 0.79 CYP1A2 (0.60) CYP1A2CYP2D6HPGDCYP2C19ATM
SCHEMBL28736779 0.79 CNR2 (0.59) VCAM1ATMTDP1L3MBTL1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 EP disclosed
US-20240392186-A1 METAL COMPLEXES, MIXTURES, COMPOSITIONS AND ORGANIC ELECTRONIC DEVICES GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2024-11-28 US disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 WO disclosed
EP-4421080-A1 METAL COMPLEX, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC COMPONENT Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2024-08-28 EP disclosed
WO-2023065614-A1 METAL COMPLEX, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC COMPONENT 广州华睿光电材料有限公司 2023-04-27 WO disclosed