Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 18/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006588 | 0.89 | SMYD3 (0.65) | SMYD3ANPEP | |
| SCHEMBL30375783 | 0.89 | SMYD3 (0.65) | SMYD3ANPEP | |
| SCHEMBL25315485 | 0.89 | SMYD3 (0.65) | SMYD3ANPEP | |
| SCHEMBL30376200 | 0.89 | SMYD3 (0.65) | SMYD3ANPEP | |
| SCHEMBL25312089 | 0.88 | SMYD3 (0.54) | SMYD3ANPEPAKT1 | |
| SCHEMBL25312087 | 0.88 | SMYD3 (0.54) | SMYD3ANPEPAKT1 | |
| SCHEMBL25312585 | 0.87 | SMYD3 (0.55) | SMYD3ANPEPAKT1 | |
| SCHEMBL25312590 | 0.87 | SMYD3 (0.55) | SMYD3ANPEPAKT1 | |
| SCHEMBL25313196 | 0.82 | ANPEP (0.57) | SMYD3ANPEPAKT1 | |
| SCHEMBL25311225 | 0.82 | SMYD3 (0.52) | SMYD3ANPEPAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4157858-A2 | SMALL MOLECULE INHIBITORS OF GRK5 AND GRK5 SUBFAMILY MEMBERS AND USES THEREOF | The Regents of The University of Michigan (US) | 2023-04-05 | — | — | EP | disclosed |