SCHEMBL30376537

SCHEMBL30376537

CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 1/20 0.48
▸ ERAP1 Q9NZ08 1/20 0.48
▸ LNPEP Q9UIQ6 1/20 0.48
▸ FOLH1 Q04609 2/20 0.45
▸ BACE1 P56817 7/20 0.44
▸ NOD1 Q9Y239 1/20 0.42
▸ CPB2 Q96IY4 3/20 0.42
▸ NPY1R P25929 1/20 0.41
▸ NPY2R P49146 1/20 0.41
▸ NPY4R P50391 1/20 0.41
▸ PTPN1 P18031 1/20 0.41
▸ CTSD P07339 1/20 0.41
▸ NMT2 O60551 1/20 0.40
▸ NMT1 P30419 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31211799 0.95 ERAP2 (0.51) ERAP2ERAP1LNPEPFOLH1NOD1
SCHEMBL31750957 0.95 BACE1 (0.48) ERAP2ERAP1LNPEPFOLH1BACE1
SCHEMBL29760983 0.95 BACE1 (0.48) ERAP2ERAP1LNPEPFOLH1BACE1
SCHEMBL31042502 0.95 BACE1 (0.48) ERAP2ERAP1LNPEPFOLH1BACE1
SCHEMBL29777802 0.92 FOLH1 (0.55) ERAP2ERAP1LNPEPFOLH1BACE1
SCHEMBL29777885 0.92 FOLH1 (0.48) FOLH1BACE1NOD1CPB2CTSD
SCHEMBL30734094 0.92 FOLH1 (0.48) FOLH1BACE1NOD1CPB2CTSD
SCHEMBL30193776 0.91 ERAP2 (0.54) ERAP2ERAP1LNPEPFOLH1NOD1
SCHEMBL31412174 0.91 ERAP2 (0.54) ERAP2ERAP1LNPEPFOLH1NOD1
SCHEMBL30193296 0.91 ERAP2 (0.54) ERAP2ERAP1LNPEPFOLH1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11633459-B2 GIP derivatives and uses thereof NOVO NORDISK A/S (DK) 2023-04-25 — — US claimed
US-20240190938-A1 GIP DERIVATIVES AND USES THEREOF NOVO NORDISK AS (DK) 2024-06-13 — — US disclosed
US-11633459-B2 GIP derivatives and uses thereof NOVO NORDISK A/S (DK) 2023-04-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633459-B2 GIP derivatives and uses thereof GIPR, GLP1R, GPR119 ERAP2 342/4885ERAP1 216/4885LNPEP 217/4885
US-20240190938-A1 GIP DERIVATIVES AND USES THEREOF GIPR, GLP1R, GPR119 ERAP2 342/4885ERAP1 216/4885LNPEP 217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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