Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099915 | 1.00 | HIF1A (0.45) | HIF1ATGM2P4HBCA1CA2 | |
| SCHEMBL16123326 | 0.86 | PDGFRB (0.42) | HIF1ATGM2P4HBCA1CA2 | |
| SCHEMBL16095549 | 0.86 | HIF1A (0.42) | HIF1AP4HBCA1CA2CA9 | |
| SCHEMBL16101030 | 0.84 | HIF1A (0.43) | HIF1ATGM2BTKDGAT1JAK3 | |
| SCHEMBL30380339 | 0.84 | HIF1A (0.43) | HIF1ATGM2BTKDGAT1JAK3 | |
| SCHEMBL30226989 | 0.83 | CA1 (0.47) | HIF1ATGM2P4HBCA1CA2 | |
| SCHEMBL16101168 | 0.83 | HIF1A (0.40) | HIF1ATGM2BTKDGAT1JAK3 | |
| SCHEMBL16100693 | 0.82 | HIF1A (0.39) | HIF1AP4HBCA1CA2CA9 | |
| SCHEMBL21198519 | 0.81 | GAA (0.41) | HIF1ATGM2DGAT1EGFRMAPK3 | |
| SCHEMBL16101102 | 0.80 | HIF1A (0.40) | HIF1ATGM2BTKDGAT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4167982-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |