Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | MAOB | P27338 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25199755 | 1.00 | MAPT (0.72) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL25189616 | 0.91 | MAPT (0.60) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL30384304 | 0.91 | MAPT (0.60) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL30383808 | 0.88 | MAPT (0.78) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL25192237 | 0.88 | MAPT (0.78) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL25219772 | 0.86 | MAOB (0.61) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL30383661 | 0.86 | MAOB (0.61) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL25199703 | 0.84 | MAPT (1.00) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL25200519 | 0.84 | MAPT (1.00) | MAPTKDM4ELMNAMAOBALDH1A1 | |
| SCHEMBL2509369 | 0.83 | MAOB (0.63) | MAPTKDM4ELMNAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |