SCHEMBL25189616

SCHEMBL25189616

O=C(/C=C/c1ccc(CN2CCOCC2)c(O)c1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.60
▸ KDM4E B2RXH2 3/20 0.60
▸ LMNA P02545 1/20 0.60
▸ SMN1; SMN2 Q16637 3/20 0.58
▸ MAOB P27338 6/20 0.58
▸ NPC1 O15118 4/20 0.58
▸ RAB9A P51151 4/20 0.58
▸ ALDH1A1 P00352 3/20 0.58
▸ L3MBTL1 Q9Y468 2/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ RECQL P46063 1/20 0.58
▸ MAPK1 P28482 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ MAOA P21397 2/20 0.49
▸ NPSR1 Q6W5P4 1/20 0.49
▸ HSP90AA1 P07900 1/20 0.48
▸ ITGB2 P05107 1/20 0.48
▸ ICAM1 P05362 1/20 0.48
▸ ITGAL P20701 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384304 1.00 MAPT (0.60) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL25199755 0.91 MAPT (0.72) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL30382297 0.91 MAPT (0.72) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL25214691 0.90 MAOB (0.56) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL30383725 0.90 MAOB (0.56) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL25192237 0.86 MAPT (0.78) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL30383808 0.86 MAPT (0.78) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL2509369 0.83 MAOB (0.63) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL2509364 0.83 MAOB (0.63) MAPTKDM4ELMNASMN1; SMN2MAOB
SCHEMBL13339132 0.83 MAOB (0.63) MAPTKDM4ELMNASMN1; SMN2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885KDM4E 1732/4885LMNA 1180/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KDM4E 2652/4885LMNA 1817/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KDM4E 2652/4885LMNA 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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