Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25196048 | 1.00 | KEAP1 (0.56) | KEAP1NFE2L2KDM4ELMNAMAPT | |
| SCHEMBL25205904 | 0.99 | KEAP1 (0.55) | KEAP1NFE2L2KDM4ELMNAMAPT | |
| SCHEMBL30383426 | 0.99 | KEAP1 (0.55) | KEAP1NFE2L2KDM4ELMNAMAPT | |
| SCHEMBL25192270 | 0.92 | CXCL12 (0.65) | KEAP1NFE2L2KDM4ELMNAMAPT | |
| SCHEMBL25198003 | 0.91 | KEAP1 (0.69) | KEAP1NFE2L2KDM4ELMNAMAPT | |
| SCHEMBL30383954 | 0.91 | KEAP1 (0.69) | KEAP1NFE2L2KDM4ELMNAMAPT | |
| SCHEMBL25223384 | 0.91 | KEAP1 (0.69) | KEAP1NFE2L2KDM4ELMNAMAPT | |
| SCHEMBL30382661 | 0.84 | KDM4E (0.64) | KDM4ELMNAMAPTCXCL12TUBB4A | |
| SCHEMBL25279664 | 0.84 | KDM4E (0.64) | KDM4ELMNAMAPTCXCL12TUBB4A | |
| SCHEMBL25184985 | 0.83 | MAPT (0.63) | KDM4ELMNAMAPTCXCL12TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |