Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 14/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803584 | 0.82 | RIPK1 (0.75) | RIPK1 | |
| SCHEMBL23803580 | 0.81 | RIPK1 (0.56) | RIPK1CLK1CLK2DYRK1A | |
| SCHEMBL23803519 | 0.79 | RIPK1 (0.68) | RIPK1 | |
| SCHEMBL23803527 | 0.76 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL23803566 | 0.76 | RIPK1 (0.50) | RIPK1CLK1CLK2DYRK1A | |
| SCHEMBL23803548 | 0.76 | RIPK1 (0.31) | RIPK1 | |
| SCHEMBL23803550 | 0.75 | RIPK1 (0.49) | RIPK1CLK1CLK2DYRK1A | |
| SCHEMBL23819879 | 0.73 | RIPK1 (0.66) | RIPK1 | |
| SCHEMBL23819887 | 0.71 | RIPK1 (0.46) | RIPK1CLK1CLK2DYRK1A | |
| SCHEMBL23803524 | 0.71 | RIPK1 (0.69) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272272-B | RIP1 inhibitors | 圣瑞诺有限公司 | 2023-04-07 | — | — | CN | disclosed |