SCHEMBL30383140

SCHEMBL30383140

Cc1ccc(C(=O)/C=C/c2ccc(CN3CCCCC3)c(O)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 8/20 0.60
▸ MAPT P10636 5/20 0.51
▸ KDM4E B2RXH2 3/20 0.51
▸ LMNA P02545 2/20 0.51
▸ POLB P06746 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ CXCL12 P48061 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ JAK2 O60674 1/20 0.51
▸ USP2 O75604 1/20 0.51
▸ GAA P10253 1/20 0.51
▸ THRB P10828 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ ALOX12 P18054 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ MAOA P21397 2/20 0.50
▸ RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25200417 1.00 MAOB (0.60) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25198821 0.90 MAOB (0.61) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25194688 0.89 MAOB (0.58) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25194904 0.89 MAOB (0.57) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL30383302 0.88 MAPT (0.63) MAOBMAPTKDM4ELMNAALDH1A1
SCHEMBL16510790 0.88 MAPT (0.63) MAOBMAPTKDM4ELMNAALDH1A1
SCHEMBL25190992 0.88 MAPT (0.63) MAOBMAPTKDM4ELMNAALDH1A1
SCHEMBL30383725 0.87 MAOB (0.56) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25214691 0.87 MAOB (0.56) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25198751 0.87 MAPT (0.64) MAOBMAPTKDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
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