SCHEMBL25200417

SCHEMBL25200417

Cc1ccc(C(=O)/C=C/c2ccc(CN3CCCCC3)c(O)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 8/20 0.60
▸ MAPT P10636 5/20 0.51
▸ KDM4E B2RXH2 3/20 0.51
▸ LMNA P02545 2/20 0.51
▸ POLB P06746 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ CXCL12 P48061 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ JAK2 O60674 1/20 0.51
▸ USP2 O75604 1/20 0.51
▸ GAA P10253 1/20 0.51
▸ THRB P10828 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ ALOX12 P18054 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ MAOA P21397 2/20 0.50
▸ RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383140 1.00 MAOB (0.60) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25198821 0.90 MAOB (0.61) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25194688 0.89 MAOB (0.58) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25194904 0.89 MAOB (0.57) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL30383302 0.88 MAPT (0.63) MAOBMAPTKDM4ELMNAALDH1A1
SCHEMBL16510790 0.88 MAPT (0.63) MAOBMAPTKDM4ELMNAALDH1A1
SCHEMBL25190992 0.88 MAPT (0.63) MAOBMAPTKDM4ELMNAALDH1A1
SCHEMBL30383725 0.87 MAOB (0.56) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25214691 0.87 MAOB (0.56) MAOBMAPTKDM4ELMNAPOLB
SCHEMBL25198751 0.87 MAPT (0.64) MAOBMAPTKDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAOB 1004/4885MAPT 3297/4885KDM4E 1732/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAPT 3512/4885KDM4E 2652/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAOB 2435/4885MAPT 3512/4885KDM4E 2652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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