Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.59 |
| ▸ | TUBB | P07437 | 1/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25192148 | 1.00 | MAPT (0.67) | MAPTNPC1RAB9APTPN1LMNA | |
| SCHEMBL30383417 | 1.00 | MAPT (0.67) | MAPTNPC1RAB9APTPN1LMNA | |
| SCHEMBL25190579 | 1.00 | MAPT (0.67) | MAPTNPC1RAB9APTPN1LMNA | |
| SCHEMBL19782818 | 0.91 | MAPT (0.67) | MAPTNPC1RAB9APTPN1KDR | |
| SCHEMBL25219790 | 0.91 | MAPT (0.67) | MAPTNPC1RAB9APTPN1KDR | |
| SCHEMBL25205394 | 0.90 | PTPN1 (0.66) | PTPN1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL30382653 | 0.90 | PTPN1 (0.66) | PTPN1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL25200308 | 0.90 | PTPN1 (0.66) | PTPN1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL25195194 | 0.90 | PTPN1 (0.66) | PTPN1LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL17054281 | 0.84 | MAPT (0.66) | MAPTNPC1RAB9APTPN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |