Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | MAOA | P21397 | 9/20 | 0.74 |
| ▸ | MAOB | P27338 | 9/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25194887 | 1.00 | MAPT (1.00) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL6263785 | 1.00 | MAPT (1.00) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL6263787 | 1.00 | MAPT (1.00) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL30277220 | 1.00 | MAPT (1.00) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL30792835 | 0.90 | MAPT (0.82) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL25219836 | 0.87 | MAOB (0.89) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL25191373 | 0.87 | MAOB (0.89) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL25233412 | 0.87 | MAOB (0.89) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL25195966 | 0.87 | MAOB (0.89) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL25196735 | 0.85 | MAPT (0.74) | MAPTKMT2AMAPK1MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |