SCHEMBL6263787

SCHEMBL6263787

CN(C)c1ccc(C=CC(=O)c2ccccc2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 1.00
KMT2A Q03164 5/20 1.00
MAPK1 P28482 4/20 1.00
MEN1 O00255 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
NPC1 O15118 3/20 1.00
RAB9A P51151 2/20 1.00
MAOA P21397 9/20 0.74
MAOB P27338 9/20 0.74
KDM4E B2RXH2 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
ALDH1A1 P00352 1/20 0.69
TP53 P04637 1/20 0.69
CYP3A4 P08684 1/20 0.69
HPGD P15428 1/20 0.69
ALOX15 P16050 1/20 0.69
ALOX12 P18054 1/20 0.69
CYP2C19 P33261 2/20 0.69
BCHE P06276 1/20 0.69
L3MBTL1 Q9Y468 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25194887 1.00 MAPT (1.00) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL30383370 1.00 MAPT (1.00) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL6263785 1.00 MAPT (1.00) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL30277220 1.00 MAPT (1.00) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL30792835 0.90 MAPT (0.82) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL25219836 0.87 MAOB (0.89) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL25191373 0.87 MAOB (0.89) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL25233412 0.87 MAOB (0.89) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL25195966 0.87 MAOB (0.89) MAPTKMT2AMAPK1MEN1TDP1
SCHEMBL25196735 0.85 MAPT (0.74) MAPTKMT2AMAPK1MEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023181073-A1 MOLECULAR SINGLE-CRYSTAL PHOTONIC MICRO-RESONATORS AND METHOD OF FABRICATING THEREOF UNIVERSITY OF HYDERABAD (IN) 2023-09-28 WO claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
CN-115745936-B Fluorescent compound, preparation method thereof and application of fluorescent compound as fluorescent probe 中国科学院大连化学物理研究所 2024-02-23 CN disclosed
WO-2023181073-A1 MOLECULAR SINGLE-CRYSTAL PHOTONIC MICRO-RESONATORS AND METHOD OF FABRICATING THEREOF UNIVERSITY OF HYDERABAD (IN) 2023-09-28 WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
CN-115745936-A Fluorescent compound, preparation method thereof and application of fluorescent compound as fluorescent probe 中国科学院大连化学物理研究所 2023-03-07 CN disclosed
CN-112110968-B Aggregation-induced fluorescence molecule modified nucleotide and application thereof in DNA sequencing and SNPs detection 北京师范大学 2021-06-15 CN disclosed
CN-112110968-A Aggregation-induced fluorescence molecule modified nucleotide and application thereof in DNA sequencing and SNPs detection 北京师范大学 2020-12-22 CN disclosed
US-20020008465-A1 Novel organic boron compound, process for producing the compound and organic luminescnece device using the compound CANON KABUSHIKI KAISHA (JP) 2002-01-24 US disclosed
EP-1138683-A2 Novel organic boron compound, process for producing the compound and organic luminescence device using the compound CANON KABUSHIKI KAISHA (JP) 2001-10-04 EP disclosed
US-4571409-A ANTIARRHYTHMIA AGENTS BASF AKTIENGESELLSCHAFT (DE) 1986-02-18 US disclosed
EP-0075207-B1 AMINOPROPANOL DERIVATIVES OF 2-HYDROXY-BETA-PHENYL PROPIOPHENONES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM BASF Aktiengesellschaft (DE) 1986-02-05 EP disclosed
US-4540697-A ANTIARRHYTHMIA AGENTS BASF AKTIENGESELLSCHAFT (DE) 1985-09-10 US disclosed
US-4461907-A Amino-substituted flavans useful as anti-viral agents BURROUGHS WELLCOME CO. 1984-07-24 US disclosed
EP-0075207-A2 Aminopropanol derivatives of 2-hydroxy-beta-phenyl propiophenones, processes for their preparation and therapeutic agents containing them BASF Aktiengesellschaft (DE) 1983-03-30 EP disclosed
EP-0004579-B1 FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM THE WELLCOME FOUNDATION LIMITED (GB) 1982-08-18 EP disclosed
EP-0051061-A2 Novel intermediates and process for their preparation THE WELLCOME FOUNDATION LIMITED (GB) 1982-05-05 EP disclosed
EP-0004579-A1 Flavans, process for their preparation and pharmaceutical compositions containing them THE WELLCOME FOUNDATION LIMITED (GB) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B MAPT 3297/4885KMT2A 2792/4885MAPK1 3352/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KMT2A 3188/4885MAPK1 3412/4885
US-20020008465-A1 Novel organic boron compound, process for producing the compound and organic luminescnece device using the compound ARL1, RUVBL1, ARRB1 MAPT 4397/4885KMT2A 3420/4885MAPK1 106/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 MAPT 3512/4885KMT2A 3188/4885MAPK1 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.