Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | TOP2A | P11388 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208076 | 1.00 | MAPT (0.68) | MAPTLMNAKDM4EPOLBNPSR1 | |
| SCHEMBL11342200 | 0.88 | LMNA (0.69) | MAPTLMNAKDM4EPOLBTOP2A | |
| SCHEMBL11342203 | 0.88 | LMNA (0.69) | MAPTLMNAKDM4EPOLBTOP2A | |
| SCHEMBL30384277 | 0.86 | CXCL12 (0.74) | MAPTLMNAKDM4EPOLBTOP2A | |
| SCHEMBL28606019 | 0.86 | CXCL12 (0.74) | CXCL12 | |
| SCHEMBL30384133 | 0.86 | CXCL12 (0.74) | MAPTLMNAKDM4EPOLBTOP2A | |
| SCHEMBL25216640 | 0.86 | CXCL12 (0.74) | MAPTLMNAKDM4EPOLBTOP2A | |
| SCHEMBL25221493 | 0.86 | MAPT (0.73) | MAPTLMNAKDM4EPOLBNPSR1 | |
| SCHEMBL25219819 | 0.86 | CXCL12 (0.74) | MAPTLMNAKDM4EPOLBTOP2A | |
| SCHEMBL30383313 | 0.86 | MAPT (0.73) | MAPTLMNAKDM4EPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |