Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 7/20 | 0.61 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.58 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | P4HB | P07237 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25198751 | 1.00 | MAPT (0.64) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL30383302 | 0.99 | MAPT (0.63) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL16510790 | 0.99 | MAPT (0.63) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL25190992 | 0.99 | MAPT (0.63) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL16499491 | 0.92 | MAOB (0.62) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL25200582 | 0.92 | MAOB (0.62) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL16499487 | 0.92 | MAOB (0.62) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL25192237 | 0.91 | MAPT (0.78) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL30383808 | 0.91 | MAPT (0.78) | MAPTALDH1A1KDM4ERECQLMAOB | |
| SCHEMBL25200417 | 0.87 | MAOB (0.60) | MAPTALDH1A1KDM4ERECQLMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |