Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.59 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204086 | 1.00 | MAOB (0.64) | MAOBCXCL12CYP3A4HSPD1PKM | |
| SCHEMBL30383107 | 1.00 | MAOB (0.64) | MAOBCXCL12CYP3A4HSPD1PKM | |
| SCHEMBL25208851 | 1.00 | MAOB (0.64) | MAOBCXCL12CYP3A4HSPD1PKM | |
| SCHEMBL25209746 | 0.88 | MAOB (0.64) | MAOBCXCL12CYP3A4HSPD1PKM | |
| SCHEMBL25200404 | 0.88 | BACE1 (0.68) | MAOBCXCL12CYP3A4HSPD1PKM | |
| SCHEMBL30384517 | 0.88 | CXCL12 (0.80) | MAOBCXCL12DHODHMAPTCYP1B1 | |
| SCHEMBL25221567 | 0.88 | CXCL12 (0.80) | MAOBCXCL12DHODHMAPTCYP1B1 | |
| SCHEMBL25209522 | 0.88 | CXCL12 (0.80) | MAOBCXCL12DHODHMAPTCYP1B1 | |
| SCHEMBL25198501 | 0.88 | BACE1 (0.68) | MAOBCXCL12CYP3A4HSPD1PKM | |
| SCHEMBL30383358 | 0.88 | BACE1 (0.68) | MAOBCXCL12CYP3A4HSPD1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |