SCHEMBL25200404

SCHEMBL25200404

O=C(/C=C/c1ccc(O)c(Cl)c1)c1ccc(O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 1/20 0.68
▸ CXCL12 P48061 3/20 0.67
▸ MAOB P27338 2/20 0.67
▸ F3 P13726 1/20 0.67
▸ XDH P47989 1/20 0.65
▸ MAPT P10636 3/20 0.63
▸ RAB9A P51151 3/20 0.63
▸ MITF O75030 1/20 0.63
▸ RECQL P46063 1/20 0.63
▸ NPSR1 Q6W5P4 1/20 0.63
▸ GUSB P08236 1/20 0.61
▸ DHODH Q02127 1/20 0.59
▸ TERT O14746 1/20 0.59
▸ SNCA P37840 1/20 0.59
▸ ESR1 P03372 1/20 0.58
▸ ESR2 Q92731 1/20 0.58
▸ POLB P06746 1/20 0.58
▸ MAOA P21397 1/20 0.58
▸ CXCR4 P61073 1/20 0.57
▸ CYP3A4 P08684 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383358 1.00 BACE1 (0.68) BACE1CXCL12MAOBF3XDH
SCHEMBL25198501 1.00 BACE1 (0.68) BACE1CXCL12MAOBF3XDH
SCHEMBL25209522 0.91 CXCL12 (0.80) CXCL12MAOBMAPTDHODHTERT
SCHEMBL25221567 0.91 CXCL12 (0.80) CXCL12MAOBMAPTDHODHTERT
SCHEMBL30384517 0.91 CXCL12 (0.80) CXCL12MAOBMAPTDHODHTERT
SCHEMBL7304255 0.89 PTGS2 (0.69) CXCL12MAOBF3XDHMAPT
SCHEMBL31233368 0.89 PTGS2 (0.69) CXCL12MAOBF3XDHMAPT
SCHEMBL25199743 0.89 PTGS2 (0.69) CXCL12MAOBF3XDHMAPT
SCHEMBL7308126 0.89 PTGS2 (0.69) CXCL12MAOBF3XDHMAPT
SCHEMBL30383198 0.89 PTGS2 (0.69) CXCL12MAOBF3XDHMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B BACE1 712/4885CXCL12 399/4885MAOB 1004/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 BACE1 1486/4885CXCL12 287/4885MAOB 2435/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 BACE1 1486/4885CXCL12 287/4885MAOB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback