SCHEMBL30384249

SCHEMBL30384249

Cc1cc(/C=C/C(=O)c2ccc(C(F)(F)F)cc2)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CXCL12 P48061 2/20 0.71
CYP1A1 P04798 8/20 0.68
CYP1B1 Q16678 8/20 0.68
P4HB P07237 2/20 0.66
MAOB P27338 4/20 0.60
TERT O14746 1/20 0.52
MAPT P10636 1/20 0.52
SNCA P37840 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3972646 1.00 CXCL12 (0.71) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL3972645 1.00 CXCL12 (0.71) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL30384684 1.00 CXCL12 (0.71) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL3732308 0.86 CYP1A1 (0.68) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL3967732 0.86 CYP1A1 (0.68) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL3967735 0.86 CYP1A1 (0.68) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL31233310 0.84 BACE1 (0.68) CXCL12P4HBMAOBTERTMAPT
SCHEMBL14545763 0.84 CXCL12 (0.70) CXCL12CYP1B1MAOBTERTMAPT
SCHEMBL25208840 0.84 CXCL12 (0.67) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL25193898 0.84 CXCL12 (0.67) CXCL12CYP1A1CYP1B1P4HBMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed