SCHEMBL3972645

SCHEMBL3972645

Cc1cc(/C=C/C(=O)c2ccc(C(F)(F)F)cc2)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CXCL12 P48061 2/20 0.71
CYP1A1 P04798 8/20 0.68
CYP1B1 Q16678 8/20 0.68
P4HB P07237 2/20 0.66
MAOB P27338 4/20 0.60
TERT O14746 1/20 0.52
MAPT P10636 1/20 0.52
SNCA P37840 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3972646 1.00 CXCL12 (0.71) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL30384684 1.00 CXCL12 (0.71) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL30384249 1.00 CXCL12 (0.71) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL3732308 0.86 CYP1A1 (0.68) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL3967732 0.86 CYP1A1 (0.68) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL3967735 0.86 CYP1A1 (0.68) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL31233310 0.84 BACE1 (0.68) CXCL12P4HBMAOBTERTMAPT
SCHEMBL14545763 0.84 CXCL12 (0.70) CXCL12CYP1B1MAOBTERTMAPT
SCHEMBL25208840 0.84 CXCL12 (0.67) CXCL12CYP1A1CYP1B1P4HBMAOB
SCHEMBL25193898 0.84 CXCL12 (0.67) CXCL12CYP1A1CYP1B1P4HBMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-7566737-B2 Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients GENFIT (FR) 2009-07-28 US disclosed
US-7566737-B2 Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients GENFIT (FR) 2009-07-28 US disclosed
US-7566737-B2 Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients GENFIT (FR) 2009-07-28 US disclosed
US-20070032543-A1 Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients GENFIT (FR) 2007-02-08 US disclosed
US-20070032543-A1 Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients GENFIT (FR) 2007-02-08 US disclosed
US-20070032543-A1 Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients GENFIT (FR) 2007-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032543-A1 Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients PSEN1, BACE1, PSEN2 CXCL12 361/4885CYP1A1 958/4885CYP1B1 751/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CXCL12 399/4885CYP1A1 696/4885CYP1B1 230/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CXCL12 287/4885CYP1A1 1747/4885CYP1B1 1027/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CXCL12 287/4885CYP1A1 1747/4885CYP1B1 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.