SCHEMBL30384328

SCHEMBL30384328

O=C(O)COc1ccc(C(=O)C=Cc2cccc(C(=O)O)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.62
▸ MEN1 O00255 2/20 0.62
▸ P4HB P07237 4/20 0.58
▸ MAOB P27338 2/20 0.56
▸ MAOA P21397 1/20 0.56
▸ NPC1 O15118 2/20 0.55
▸ RAB9A P51151 2/20 0.55
▸ POLB P06746 1/20 0.55
▸ BLM P54132 1/20 0.55
▸ GPR35 Q9HC97 1/20 0.55
▸ CYSLTR2 Q9NS75 2/20 0.54
▸ BCHE P06276 6/20 0.53
▸ MAPT P10636 1/20 0.53
▸ ACHE P22303 5/20 0.52
▸ KEAP1 Q14145 1/20 0.50
▸ NFE2L2 Q16236 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11451255 1.00 KMT2A (0.62) KMT2AMEN1P4HBMAOBMAOA
SCHEMBL11451254 1.00 KMT2A (0.62) KMT2AMEN1P4HBMAOBMAOA
SCHEMBL25189336 0.92 KMT2A (0.68) KMT2AMEN1MAOBMAOANPC1
SCHEMBL11452481 0.90 KMT2A (0.65) KMT2AMEN1MAOBMAOANPC1
SCHEMBL11452485 0.90 KMT2A (0.65) KMT2AMEN1MAOBMAOANPC1
SCHEMBL30383113 0.90 KMT2A (0.65) KMT2AMEN1MAOBMAOANPC1
SCHEMBL25195879 0.88 MEN1 (0.64) KMT2AMEN1P4HBMAOBMAOA
SCHEMBL31233321 0.88 MEN1 (0.64) KMT2AMEN1P4HBMAOBMAOA
SCHEMBL25212073 0.86 KMT2A (0.76) KMT2AMEN1MAOBMAOANPC1
SCHEMBL25192238 0.86 KMT2A (0.76) KMT2AMEN1MAOBMAOANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
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