SCHEMBL25189336

SCHEMBL25189336

O=C(O)COc1ccc(C(=O)/C=C/c2cccc(/C=C/C(=O)c3ccc(OCC(=O)O)cc3)c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.68
▸ MEN1 O00255 3/20 0.68
▸ MAOB P27338 3/20 0.62
▸ MAOA P21397 1/20 0.62
▸ NPC1 O15118 2/20 0.59
▸ RAB9A P51151 2/20 0.59
▸ POLB P06746 1/20 0.59
▸ BLM P54132 1/20 0.59
▸ GPR35 Q9HC97 1/20 0.59
▸ BCHE P06276 6/20 0.55
▸ ACHE P22303 5/20 0.55
▸ MAPT P10636 2/20 0.55
▸ ALDH1A1 P00352 1/20 0.55
▸ HSPD1 P10809 1/20 0.55
▸ TNFRSF1A P19438 1/20 0.55
▸ HSPE1 P61604 1/20 0.55
▸ CYP1B1 Q16678 1/20 0.55
▸ KEAP1 Q14145 1/20 0.54
▸ NFE2L2 Q16236 1/20 0.54
▸ ABCG2 Q9UNQ0 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11452485 0.94 KMT2A (0.65) KMT2AMEN1MAOBMAOANPC1
SCHEMBL11452481 0.94 KMT2A (0.65) KMT2AMEN1MAOBMAOANPC1
SCHEMBL30383113 0.94 KMT2A (0.65) KMT2AMEN1MAOBMAOANPC1
SCHEMBL25195879 0.93 MEN1 (0.64) KMT2AMEN1MAOBMAOANPC1
SCHEMBL31233321 0.93 MEN1 (0.64) KMT2AMEN1MAOBMAOANPC1
SCHEMBL11451254 0.92 KMT2A (0.62) KMT2AMEN1MAOBMAOANPC1
SCHEMBL11451255 0.92 KMT2A (0.62) KMT2AMEN1MAOBMAOANPC1
SCHEMBL30384328 0.92 KMT2A (0.62) KMT2AMEN1MAOBMAOANPC1
SCHEMBL25192238 0.91 KMT2A (0.76) KMT2AMEN1MAOBMAOANPC1
SCHEMBL25212073 0.91 KMT2A (0.76) KMT2AMEN1MAOBMAOANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B KMT2A 2792/4885MEN1 3367/4885MAOB 1004/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885MEN1 2457/4885MAOB 2435/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 KMT2A 3188/4885MEN1 2457/4885MAOB 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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