SCHEMBL30384339

SCHEMBL30384339

O=C(C=Cc1ccc(OCc2ccccc2)cc1)c1c(O)cc(OCc2ccccc2)cc1OCc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 3/20 0.80
▸ SLC5A2 P31639 3/20 0.80
▸ ABCG2 Q9UNQ0 2/20 0.65
▸ APP P05067 1/20 0.64
▸ GSK3B P49841 4/20 0.61
▸ BACE1 P56817 4/20 0.61
▸ MAOB P27338 2/20 0.59
▸ TP53 P04637 2/20 0.58
▸ MAPT P10636 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ CYP3A4 P08684 1/20 0.58
▸ ATM Q13315 1/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ PDE4A P27815 1/20 0.53
▸ PDE4B Q07343 1/20 0.53
▸ PDE4C Q08493 1/20 0.53
▸ PDE4D Q08499 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13657210 1.00 SLC5A1 (0.80) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL4883627 1.00 SLC5A1 (0.80) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL30384783 1.00 SLC5A1 (0.80) SLC5A1SLC5A2ABCG2APPGSK3B
Ethane SCHEMBL25205522 0.98 SLC5A1 (0.77) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL15681494 0.97 SLC5A1 (0.75) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL30383800 0.95 SLC5A1 (0.72) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL1727983 0.95 SLC5A1 (0.72) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL1727986 0.95 SLC5A1 (0.72) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL25234616 0.93 SLC5A1 (0.70) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL17237771 0.93 SLC5A1 (0.70) SLC5A1SLC5A2ABCG2APPGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
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