SCHEMBL4883627

SCHEMBL4883627

O=C(C=Cc1ccc(OCc2ccccc2)cc1)c1c(O)cc(OCc2ccccc2)cc1OCc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ SLC5A1 P13866 3/20 0.80
▸ SLC5A2 P31639 3/20 0.80
▸ ABCG2 Q9UNQ0 2/20 0.65
▸ APP P05067 1/20 0.64
▸ GSK3B P49841 4/20 0.61
▸ BACE1 P56817 4/20 0.61
▸ MAOB P27338 2/20 0.59
▸ TP53 P04637 2/20 0.58
▸ MAPT P10636 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ CYP3A4 P08684 1/20 0.58
▸ ATM Q13315 1/20 0.58
▸ HSD17B10 Q99714 1/20 0.58
▸ KDM4E B2RXH2 1/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ PDE4A P27815 1/20 0.53
▸ PDE4B Q07343 1/20 0.53
▸ PDE4C Q08493 1/20 0.53
▸ PDE4D Q08499 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384339 1.00 SLC5A1 (0.80) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL13657210 1.00 SLC5A1 (0.80) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL30384783 1.00 SLC5A1 (0.80) SLC5A1SLC5A2ABCG2APPGSK3B
Ethane SCHEMBL25205522 0.98 SLC5A1 (0.77) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL15681494 0.97 SLC5A1 (0.75) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL30383800 0.95 SLC5A1 (0.72) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL1727983 0.95 SLC5A1 (0.72) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL1727986 0.95 SLC5A1 (0.72) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL25234616 0.93 SLC5A1 (0.70) SLC5A1SLC5A2ABCG2APPGSK3B
SCHEMBL17237771 0.93 SLC5A1 (0.70) SLC5A1SLC5A2ABCG2APPGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
EP-2981260-B1 NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS SPHAERA PHARMA PRIVATE LTD (IN) 2021-01-13 — — EP disclosed
US-9975869-B2 Analogues of epicatechin and related polyphenols SPHAERA PHARMA PVT. LTD. (IN) 2018-05-22 — — US disclosed
US-20160039781-A1 NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS SPHAERA PHARMA PVT. LTD. (SG) 2016-02-11 — — US disclosed
US-20080269144-A1 Synthesis of Inhibitors of P90Rsk UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2008-10-30 — — US disclosed
EP-1845778-A2 SYNTHESIS OF INHIBITORS OF P90RSK UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2007-10-24 — — EP disclosed
WO-2006086103-A2 SYNTHESIS OF INHIBITORS OF P90RSK UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2006-08-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269144-A1 Synthesis of Inhibitors of P90Rsk RAF1, KSR1, STK10 SLC5A1 3010/4885SLC5A2 3842/4885ABCG2 944/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B SLC5A1 3752/4885SLC5A2 4208/4885ABCG2 1606/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885ABCG2 3622/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885ABCG2 3622/4885
US-20160039781-A1 NOVEL ANALOGUES OF EPICATECHIN AND RELATED POLYPHENOLS PGC, TEAD3, TEAD4 SLC5A1 3109/4885SLC5A2 2563/4885ABCG2 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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