Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.97 |
| ▸ | TP53 | P04637 | 2/20 | 0.97 |
| ▸ | ATM | Q13315 | 1/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.97 |
| ▸ | MAOA | P21397 | 2/20 | 0.82 |
| ▸ | MAOB | P27338 | 2/20 | 0.82 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.82 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.81 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.81 |
| ▸ | DPP4 | P27487 | 1/20 | 0.81 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.81 |
| ▸ | RELA | Q04206 | 1/20 | 0.81 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.81 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flavokawain B SCHEMBL25185055 | 0.99 | MAPT (1.00) | MAPTKMT2ACYP3A4TP53ATM | |
| Flavokawain B SCHEMBL30382640 | 0.99 | MAPT (1.00) | MAPTKMT2ACYP3A4TP53ATM | |
| Flavokawain B SCHEMBL29439356 | 0.99 | MAPT (1.00) | MAPTKMT2ACYP3A4TP53ATM | |
| Flavokawain B SCHEMBL1675987 | 0.99 | MAPT (1.00) | MAPTKMT2ACYP3A4TP53ATM | |
| Flavokawain B SCHEMBL1938260 | 0.99 | MAPT (1.00) | MAPTKMT2ACYP3A4TP53ATM | |
| Flavokawain B SCHEMBL25193713 | 0.97 | MAPT (0.97) | MAPTKMT2ACYP3A4TP53ATM | |
| Flavokawain B SCHEMBL25265211 | 0.97 | MAPT (0.97) | MAPTKMT2ACYP3A4TP53ATM | |
| Flavokawain B SCHEMBL25278514 | 0.93 | MAPT (0.88) | MAPTKMT2ACYP3A4TP53ATM | |
| Flavokawain B SCHEMBL25190550 | 0.92 | MAPT (0.86) | MAPTKMT2ACYP3A4TP53ATM | |
| SCHEMBL25192230 | 0.91 | MAPT (0.86) | MAPTKMT2ACYP3A4TP53ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | MAPT 3512/4885KMT2A 3188/4885CYP3A4 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.