Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | DDX3X | O00571 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225469 | 1.00 | MAPT (0.59) | MAPTKMT2AMEN1POLBDDX3X | |
| Dinitrophenylene SCHEMBL27410199 | 0.87 | TSHR (0.62) | MAPTKMT2AMEN1POLBDDX3X | |
| SCHEMBL14336441 | 0.83 | MAPT (0.55) | MAPTKMT2AMEN1POLBDDX3X | |
| SCHEMBL11141517 | 0.82 | KMT2A (0.56) | MAPTKMT2AMEN1POLBDDX3X | |
| SCHEMBL24076228 | 0.81 | KMT2A (0.72) | MAPTKMT2AMEN1POLBLMNA | |
| SCHEMBL11887661 | 0.81 | MAPT (0.54) | MAPTKMT2AMEN1POLBDDX3X | |
| SCHEMBL3956359 | 0.81 | MAPT (0.54) | MAPTKMT2AMEN1POLBDDX3X | |
| SCHEMBL3691338 | 0.80 | CYP19A1 (0.50) | MAPTKMT2AMEN1POLBDDX3X | |
| SCHEMBL394734 | 0.80 | KMT2A (0.67) | MAPTKMT2AMEN1POLBDDX3X | |
| SCHEMBL2053443 | 0.79 | MAPT (0.56) | MAPTKMT2AMEN1POLBDDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186074-A | Pyridazine-3-carboxamide compounds as TYK2 inhibitors | 广州费米子科技有限责任公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-111686110-B | Compounds and compositions for modulating EGFR mutant kinase activity | 株式会社柳韩洋行 | 2023-06-16 | — | — | CN | disclosed |