SCHEMBL2053443

SCHEMBL2053443

O=CCNc1cccc([N+](=O)[O-])c1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.56
MEN1 O00255 3/20 0.56
POLB P06746 3/20 0.56
KMT2A Q03164 3/20 0.56
DDX3X O00571 1/20 0.56
HTT P42858 1/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
LMNA P02545 1/20 0.53
TSHR P16473 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 5/20 0.51
ALOX12 P18054 2/20 0.50
HPGD P15428 1/20 0.50
BLM P54132 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27982248 0.85 MEN1 (0.51) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL9448739 0.85 MAPT (0.54) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL29689011 0.84 KMT2A (0.61) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL730213 0.81 MAPT (0.62) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL28211599 0.81 MAPT (0.57) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL28807504 0.81 MAPT (0.62) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL10055046 0.79 PTPRF (0.68) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL16943226 0.79 MAPT (0.56) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL30385018 0.79 MAPT (0.59) MAPTMEN1POLBKMT2ADDX3X
SCHEMBL225469 0.79 MAPT (0.59) MAPTMEN1POLBKMT2ADDX3X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015063124-A1 DYEING METHOD EMPLOYING AN EXPANDED OXIDIZING COMPOSITION L'OREAL (FR) 2015-05-07 WO disclosed
EP-2791106-A1 PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF L'OREAL (FR) 2014-10-22 EP disclosed
WO-2014102324-A1 DYEING METHOD EMPLOYING A DYE AND A CHAOTROPIC SALT L'OREAL (FR) 2014-07-03 WO disclosed
WO-2013087770-A1 PARTICULAR QUINONE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, IMPLEMENTATION PROCESS THEREFOR AND USE THEREOF L'OREAL (FR) 2013-06-20 WO disclosed
EP-2516013-A1 AGENT IN TWO OR MORE PARTS, IN EMULSION FORM, FOR DYEING AND/OR BLEACHING KERATIN FIBRES L'Oréal (FR) 2012-10-31 EP disclosed
WO-2011076665-A1 AGENT IN TWO OR MORE PARTS, IN EMULSION FORM, FOR DYEING AND/OR BLEACHING KERATIN FIBRES L'OREAL (FR) 2011-06-30 WO disclosed
EP-2194957-A2 COMPOSITION COMPRISING AT LEAST ONE AMMONIUM SALT, AQUEOUS AMMONIA AND AT LEAST ONE AMINO ACID L'Oreal (FR) 2010-06-16 EP disclosed
WO-2009050295-A2 COMPOSITION COMPRISING AT LEAST ONE AMMONIUM SALT, AQUEOUS AMMONIA AND AT LEAST ONE AMINO ACID L'OREAL (FR) 2009-04-23 WO disclosed