Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 9/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1605961 | 1.00 | CYP11B2 (0.59) | CYP11B2TDP1CYP11B1CYP19A1MAOA | |
| SCHEMBL13122291 | 0.89 | CYP11B2 (0.59) | CYP11B2TDP1CYP11B1CYP19A1MAOA | |
| SCHEMBL3674058 | 0.84 | CYP11B2 (0.61) | CYP11B2CYP11B1CYP19A1MAOASMN1; SMN2 | |
| SCHEMBL1605747 | 0.80 | CYP11B2 (0.65) | CYP11B2TDP1CYP11B1CYP19A1MAOA | |
| SCHEMBL1605877 | 0.77 | CYP11B2 (0.64) | CYP11B2TDP1CYP11B1CYP19A1MAOA | |
| SCHEMBL1606735 | 0.77 | CYP11B2 (0.64) | CYP11B2TDP1CYP11B1CYP19A1MAOA | |
| SCHEMBL1605856 | 0.76 | CYP11B2 (0.70) | CYP11B2TDP1CYP11B1CYP19A1MAOA | |
| SCHEMBL1606066 | 0.76 | CYP11B2 (0.68) | CYP11B2TDP1CYP11B1CYP19A1MAOA | |
| SCHEMBL1605235 | 0.76 | CYP11B2 (0.68) | CYP11B2TDP1CYP11B1CYP19A1MAOA | |
| SCHEMBL3685276 | 0.76 | CYP11B2 (0.68) | CYP11B2TDP1CYP11B1CYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166204-B | Cyclic peptides as inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-113166114-B | Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2023084449-A1 | DIAMINOCYCLOPENTYLPYRIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER | NOVARTIS AG (CH) | 2023-05-19 | — | — | WO | disclosed |