Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28982190 | 0.90 | SYK (0.34) | PTK6LRRK2CSNK1DTTK | |
| Trifluoroacetic Acid SCHEMBL28982169 | 0.81 | PTK6 (0.39) | PTK6SMN1; SMN2LRRK2NTRK1TTK | |
| SCHEMBL25288956 | 0.81 | PTK6 (0.48) | PTK6TTKBRAF | |
| SCHEMBL28982156 | 0.80 | PTK6 (0.43) | PTK6ALDH1A1POLBKDM4EGAA | |
| SCHEMBL22123948 | 0.80 | PTK6 (0.49) | PTK6ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL25282280 | 0.79 | PTK6 (0.47) | PTK6MALT1TTKBRAF | |
| SCHEMBL28961286 | 0.79 | PTK6 (0.47) | PTK6POLBTTKADORA3 | |
| SCHEMBL25173550 | 0.77 | PTK6 (0.42) | PTK6KDM4EGAASMN1; SMN2ADORA3 | |
| SCHEMBL28916262 | 0.76 | TTK (0.36) | PTK6KDM4EGAASMN1; SMN2KMT2A | |
| SCHEMBL25288598 | 0.76 | PTK6 (0.45) | PTK6TTKBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |