Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606956 | 1.00 | USP2 (0.47) | USP2SMN1; SMN2KMT2ACHRNB1CHRNB2 | |
| SCHEMBL1606105 | 0.86 | CYP11B2 (0.47) | USP2SMN1; SMN2CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL1606194 | 0.84 | KMT2A (0.45) | KMT2ACHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1606086 | 0.81 | CYP11B2 (0.55) | KMT2ACHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1606399 | 0.80 | NR1H2 (0.40) | KMT2ACHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1605878 | 0.79 | KMT2A (0.55) | KMT2ACHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL14603921 | 0.78 | KMT2A (0.46) | KMT2ACHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1606591 | 0.78 | KMT2A (0.54) | KMT2ACHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1605531 | 0.77 | CYP11B2 (0.69) | KMT2ACHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6125512 | 0.76 | KMT2A (0.44) | KMT2ACHRNB1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166204-B | Cyclic peptides as inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-113166114-B | Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2023084449-A1 | DIAMINOCYCLOPENTYLPYRIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER | NOVARTIS AG (CH) | 2023-05-19 | — | — | WO | disclosed |