Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 10/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | PRKACG | P22612 | 1/20 | 0.38 |
| ▸ | PRKACB | P22694 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123969 | 1.00 | PTK6 (0.48) | PTK6EGFRSYKAURKBAURKA | |
| SCHEMBL30385212 | 0.93 | PTK6 (0.50) | PTK6SYKAURKBMAPKAPK5LCK | |
| SCHEMBL22139113 | 0.92 | PTK6 (0.48) | PTK6SYKAURKBAURKAINSR | |
| SCHEMBL30172107 | 0.92 | PTK6 (0.48) | PTK6SYKAURKBAURKAINSR | |
| SCHEMBL25170422 | 0.91 | SYK (0.41) | PTK6SYKAURKBMAPKAPK5DHODH | |
| Trifluoroacetic Acid SCHEMBL30386106 | 0.90 | PTK6 (0.47) | PTK6EGFRSYKAURKBMAPKAPK5 | |
| SCHEMBL22125440 | 0.90 | PTK6 (0.59) | PTK6AURKBLCK | |
| SCHEMBL30171569 | 0.90 | PTK6 (0.59) | PTK6AURKBLCK | |
| SCHEMBL25167694 | 0.90 | PTK6 (0.47) | PTK6AURKBKDM4ECCNB2CCNE2 | |
| SCHEMBL25170375 | 0.90 | PTK6 (0.40) | PTK6SYKAURKBAURKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |