Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.37 |
| ▸ | HTR3B | O95264 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21730229 | 1.00 | PDE10A (0.39) | PDE10AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30385235 | 0.90 | HTR3A (0.38) | PDE10AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22551892 | 0.90 | HTR3A (0.38) | PDE10AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22551836 | 0.80 | PDE10A (0.36) | PDE10AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30880813 | 0.80 | PDE10A (0.36) | PDE10AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL21722602 | 0.78 | HTR3A (0.60) | PDE10AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL21730228 | 0.76 | SOS1 (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL26095748 | 0.75 | PDE10A (0.33) | PDE10AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23774619 | 0.73 | PDE10A (0.47) | PDE10AHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23774759 | 0.73 | HTR3A (0.34) | PDE10AHTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |