Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.35 |
| ▸ | LCK | P06239 | 6/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125159 | 1.00 | PTK6 (0.41) | PTK6AURKBLCKPTK2JAK2 | |
| Trifluoroacetic Acid SCHEMBL25167702 | 0.95 | PTK6 (0.37) | PTK6AURKBLCKPTK2JAK2 | |
| SCHEMBL30172036 | 0.91 | PTK2 (0.38) | PTK6PTK2JAK2JAK1TTK | |
| SCHEMBL24870930 | 0.91 | PTK2 (0.38) | PTK6PTK2JAK2JAK1TTK | |
| SCHEMBL24112463 | 0.90 | PTK6 (0.36) | PTK6AURKBLCK | |
| Formic Acid SCHEMBL30386621 | 0.89 | PTK6 (0.35) | PTK6AURKBLCK | |
| SCHEMBL24112613 | 0.88 | PTK6 (0.39) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL22153365 | 0.88 | PTK6 (0.48) | PTK6AURKBLCKJAK2JAK1 | |
| SCHEMBL24112643 | 0.88 | PTK6 (0.41) | PTK6AURKBLCKTTK | |
| SCHEMBL25176078 | 0.87 | PTK6 (0.42) | PTK6AURKBLCKJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161931-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-04-12 | — | — | EP | disclosed |