Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | SAT1 | P21673 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139003 | 0.85 | TSHR (0.67) | TSHRCYP2C19MEN1GLAKMT2A | |
| Diethylamine SCHEMBL27841769 | 0.83 | TP53 (0.53) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL975756 | 0.80 | CYP2C19 (0.42) | TSHRCYP2C19MEN1GLAKMT2A | |
| SCHEMBL7885 | 0.80 | — | — | |
| Bromide SCHEMBL25346344 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6260885 | 0.76 | — | — | |
| SCHEMBL21065744 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL11366235 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL10410334 | 0.76 | — | — | |
| SCHEMBL10904114 | 0.76 | CYP2C19 (0.62) | TSHRCYP2C19MEN1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190637-A1 | Curing Catalyst | MERCK PATENT GESELLSCHAFT (DE) | 2010-07-29 | — | — | US | claimed |
| CN-110366580-B | Method of forming encapsulated pigment slurries for waterborne topcoat coating compositions | 巴斯夫涂料有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-107207885-B | Method of forming passivated pigment slurries for waterborne topcoat coating compositions | 巴斯夫涂料有限公司 | 2020-03-03 | — | — | CN | disclosed |
| US-8586659-B2 | Redispersible surfaced-modified particles | MERCK PATENT GMBH (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20100215959-A1 | SILANES | MERCK PATENT GMBH (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20100190637-A1 | Curing Catalyst | MERCK PATENT GESELLSCHAFT (DE) | 2010-07-29 | — | — | US | disclosed |
| US-20100092761-A1 | NANOPARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2010-04-15 | — | — | US | disclosed |
| US-20100010137-A1 | REDISPERSIBLE SURFACED-MODIFIED PARTICLES | MERCK PATENT GESELLSCHAFT (DE) | 2010-01-14 | — | — | US | disclosed |
| US-20080248289-A1 | Zinc Oxide Nanoparticles | MERCK PATENT GESELLSCHAFT (DE) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100215959-A1 | SILANES | SGMS1, SGMS2, SUMO3 | TSHR 3867/4885CYP2C19 3256/4885MEN1 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.