Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.69 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.69 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.69 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.69 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.58 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.58 |
| ▸ | SRC | P12931 | 6/20 | 0.58 |
| ▸ | FLT1 | P17948 | 3/20 | 0.50 |
| ▸ | FLT4 | P35916 | 3/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CSK | P41240 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366761 | 0.82 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL1248489 | 0.82 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL8135892 | 0.73 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL24490070 | 0.73 | FGFR1 (0.63) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL5619571 | 0.71 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL6916832 | 0.70 | FGFR1 (0.63) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL19848922 | 0.69 | FGFR1 (0.80) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL15602866 | 0.69 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL1249693 | 0.69 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3EGFR | |
| SCHEMBL2470677 | 0.69 | FGFR1 (0.72) | FGFR1FGFR2FGFR4FGFR3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117982733-A | Biodegradable tissue replacement implants and uses thereof | 美国政府(由卫生和人类服务部的部长所代表) | 2024-05-07 | — | — | CN | disclosed |
| CN-113226387-B | Biodegradable tissue replacement implants and uses thereof | 美国政府(由卫生和人类服务部的部长所代表) | 2024-02-23 | — | — | CN | disclosed |
| CN-116033912-A | Retinal pigment epithelium and photoreceptor double cell aggregates and methods of use thereof | 富士胶片细胞动力公司 | 2023-04-28 | — | — | CN | disclosed |