SCHEMBL1249693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2470677	0.86	FGFR1 (0.72)	FGFR1FGFR2FGFR4FGFR3FLT1
	SCHEMBL22144559	0.83	FGFR1 (0.95)	FGFR1FGFR2FGFR4FGFR3FLT1
	SCHEMBL19848922	0.83	FGFR1 (0.80)	FGFR1FGFR2FGFR4FGFR3FLT1
	Pd-173074 SCHEMBL29828472	0.82	FGFR1 (1.00)	FGFR1FGFR2FGFR4FGFR3FLT1
	Pd-173074 SCHEMBL177946	0.82	FGFR1 (1.00)	FGFR1FGFR2FGFR4FGFR3FLT1
	SCHEMBL31648262	0.82	FGFR1 (0.76)	FGFR1FGFR2FGFR4FGFR3FLT1
	SCHEMBL3479994	0.82	FGFR1 (0.87)	FGFR1FGFR2FGFR4FGFR3FLT1
	SCHEMBL30737861	0.81	FGFR1 (1.00)	FGFR1FGFR2FGFR4FGFR3FLT1
	SCHEMBL2470675	0.81	FGFR1 (0.85)	FGFR1FGFR2FGFR4FGFR3FLT1
	SCHEMBL31648009	0.80	FGFR1 (0.78)	FGFR1FGFR2FGFR4FGFR3FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.