Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 16/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 16/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 16/20 | 1.00 |
| ▸ | PRKDC | P78527 | 16/20 | 1.00 |
| ▸ | EGFR | P00533 | 17/20 | 0.77 |
| ▸ | ABL1 | P00519 | 15/20 | 0.77 |
| ▸ | HCK | P08631 | 15/20 | 0.77 |
| ▸ | SRC | P12931 | 15/20 | 0.77 |
| ▸ | KDR | P35968 | 15/20 | 0.77 |
| ▸ | MTOR | P42345 | 15/20 | 0.77 |
| ▸ | EPHB4 | P54760 | 15/20 | 0.77 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.72 |
| ▸ | BTK | Q06187 | 2/20 | 0.71 |
| ▸ | LCK | P06239 | 1/20 | 0.71 |
| ▸ | LYN | P07948 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19335162 | 0.86 | BTK (0.80) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL19335172 | 0.84 | BTK (0.79) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL19335138 | 0.84 | BTK (0.79) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL22364036 | 0.84 | BTK (0.79) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL2360644 | 0.84 | BTK (0.79) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL14574865 | 0.84 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL30586962 | 0.83 | BTK (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL6431516 | 0.83 | BTK (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL19335163 | 0.83 | BTK (0.77) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL1317659 | 0.83 | LCK (0.73) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230111917-A1 | KINASE ANTAGONISTS | UNIV CALIFORNIA (US) | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230111917-A1 | KINASE ANTAGONISTS | MTOR, RPS6KA3, AKT3 | PIK3CD 12/4885PIK3CA 4/4885PIK3CB 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.