Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 15/20 | 0.74 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.74 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.74 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759987 | 1.00 | TGFBR1 (0.74) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| SCHEMBL12187432 | 0.92 | TGFBR1 (0.61) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| SCHEMBL29378125 | 0.85 | TGFBR1 (1.00) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| SCHEMBL373422 | 0.85 | TGFBR1 (1.00) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| SCHEMBL29358831 | 0.85 | TGFBR1 (1.00) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| Water SCHEMBL21459280 | 0.84 | TGFBR1 (0.98) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| Hydrochloric Acid SCHEMBL140197 | 0.84 | TGFBR1 (1.00) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| Hydrochloric Acid SCHEMBL29541686 | 0.84 | TGFBR1 (1.00) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| Hydrochloric Acid SCHEMBL14778775 | 0.83 | TGFBR1 (0.98) | TGFBR1MAPK14RIPK2ACVR1BTDP1 | |
| Hydrochloric Acid SCHEMBL29361019 | 0.83 | TGFBR1 (0.98) | TGFBR1MAPK14RIPK2ACVR1BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116034105-A | Heterocyclic compounds as inhibitors of casein kinase 1 delta and/or activin receptor-like kinase 5 | 亚克医药株式会社 | 2023-04-28 | — | — | CN | claimed |
| CN-116034105-B | Heterocyclic compounds as inhibitors of casein kinase 1 delta and/or activin receptor-like kinase 5 | 亚克医药株式会社 | 2025-07-18 | — | — | CN | disclosed |
| CN-116034105-A | Heterocyclic compounds as inhibitors of casein kinase 1 delta and/or activin receptor-like kinase 5 | 亚克医药株式会社 | 2023-04-28 | — | — | CN | disclosed |