Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 11/20 | 0.62 |
| ▸ | TGFBR2 | P37173 | 8/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.48 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25435271 | 1.00 | TGFBR1 (0.62) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL30387558 | 1.00 | TGFBR1 (0.62) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL30387676 | 1.00 | TGFBR1 (0.62) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL26597853 | 1.00 | TGFBR1 (0.62) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL26597847 | 1.00 | TGFBR1 (0.62) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL25207223 | 0.91 | TGFBR1 (0.54) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL25205509 | 0.91 | TGFBR1 (0.54) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL30388190 | 0.91 | TGFBR1 (0.54) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL25229820 | 0.91 | TGFBR1 (0.54) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 | |
| SCHEMBL30387552 | 0.91 | TGFBR1 (0.54) | TGFBR1TGFBR2MAPK14PRKD1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188928-B1 | SUBSTITUTED 1 H-PYRROLO[3,2-B]PYRIDIN COMPOUNDS AND METHODS OF USE THEREOF | BAYER AG (DE) | 2024-07-24 | — | — | EP | claimed |
| EP-4188928-A1 | SUBSTITUTED 1 H-PYRROLO[3,2-B]PYRIDIN COMPOUNDS AND METHODS OF USE THEREOF | Bayer Aktiengesellschaft (DE) | 2023-06-07 | — | — | EP | claimed |