SCHEMBL30388593

SCHEMBL30388593

COc1cccc(C(Cl)(c2ccccc2)c2ccccc2)c1OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 3/20 0.42
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
CA4 P22748 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
ABCB1 P08183 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.37
KCNA5 P22460 5/20 0.36
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221588 1.00 NFE2L2 (0.42) NFE2L2CA12CA1CA2CA7
Chlorotriphenylmethane SCHEMBL27667603 0.98 NFE2L2 (0.41) NFE2L2CA12CA1CA2CA7
Pyridine SCHEMBL6531371 0.91 KDM4E (0.40) NFE2L2SMN1; SMN2KCNA5TSHRNPC1
SCHEMBL2445301 0.86 SMN1; SMN2 (0.39) NFE2L2CA12CA1CA2CA7
SCHEMBL221217 0.85 CA1 (0.46) NFE2L2CA12CA1CA2CA7
SCHEMBL16675115 0.82 NFE2L2 (0.45) NFE2L2CA12CA1CA2CA7
SCHEMBL221587 0.82 CA1 (0.46) NFE2L2CA12CA1CA2CA7
SCHEMBL9013823 0.81 NFE2L2 (0.44) NFE2L2CA12CA1CA2CA7
SCHEMBL31430103 0.81 NFE2L2 (0.44) NFE2L2CA12CA1CA2CA7
SCHEMBL136230 0.81 NFE2L2 (0.44) NFE2L2CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350413-A Compound crystal form and preparation method and application thereof 天津全和诚科技有限责任公司 2025-01-24 CN claimed
CN-119350415-A Compound crystal form and preparation method and application thereof 天津全和诚科技有限责任公司 2025-01-24 CN claimed
CN-119350412-A Compound crystal form and preparation method and application thereof 天津全和诚科技有限责任公司 2025-01-24 CN claimed
CN-119350414-A Compound crystal form and preparation method and application thereof 天津全和诚科技有限责任公司 2025-01-24 CN claimed
US-20260009029-A1 COMPOUND FOR INHIBITING EXPRESSION OF LPA GENE, PHARMACEUTICAL COMPOSITION AND USE THEREOF RIGERNA THERAPEUTICS SUZHOU CO LTD (CN) 2026-01-08 US disclosed
CN-119350137-A Method for purifying 1-methoxy-2-propanol through selective covalent reaction 厦门大学 2025-01-24 CN disclosed
CN-119350413-A Compound crystal form and preparation method and application thereof 天津全和诚科技有限责任公司 2025-01-24 CN disclosed
CN-119350415-A Compound crystal form and preparation method and application thereof 天津全和诚科技有限责任公司 2025-01-24 CN disclosed
CN-119350414-A Compound crystal form and preparation method and application thereof 天津全和诚科技有限责任公司 2025-01-24 CN disclosed
CN-119350412-A Compound crystal form and preparation method and application thereof 天津全和诚科技有限责任公司 2025-01-24 CN disclosed
CN-113549121-B Preparation method of nucleoside modifier 上海兆维科技发展有限公司 2023-05-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009029-A1 COMPOUND FOR INHIBITING EXPRESSION OF LPA GENE, PHARMACEUTICAL COMPOSITION AND USE THEREOF LPAR6, LPAR2, LPAR1 NFE2L2 2798/4885CA12 3621/4885CA1 2711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.