Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 9/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 3/20 | 0.33 |
| ▸ | PYGM | P11217 | 2/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30256833 | 0.98 | PYGB (0.39) | PYGBGAAGBA1PYGLPYGM | |
| SCHEMBL31680333 | 0.98 | PYGB (0.39) | PYGBGAAGBA1PYGLPYGM | |
| SCHEMBL30368413 | 0.98 | PYGB (0.39) | PYGBGAAGBA1PYGLPYGM | |
| SCHEMBL30865647 | 0.98 | PYGB (0.39) | PYGBGAAGBA1PYGLPYGM | |
| SCHEMBL29355853 | 0.98 | PYGB (0.39) | PYGBGAAGBA1PYGLPYGM | |
| SCHEMBL23832488 | 0.98 | PYGB (0.39) | PYGBGAAGBA1PYGLPYGM | |
| Hydrochloric Acid SCHEMBL31039483 | 0.97 | PYGB (0.38) | PYGBGAAGBA1PYGLPYGM | |
| SCHEMBL29894609 | 0.97 | PYGB (0.38) | PYGBGAAGBA1PYGLPYGM | |
| Phosphoric Acid SCHEMBL30479411 | 0.88 | PYGB (0.34) | PYGBGAAGBA1 | |
| SCHEMBL31152561 | 0.87 | PYGB (0.37) | PYGBGAAGBA1PYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292616-B | Monosaccharide ligand functionalized cationic lipid compound and preparation method and application thereof | 内蒙古大学 | 2023-05-23 | — | — | CN | claimed |
| CN-113292616-B | Monosaccharide ligand functionalized cationic lipid compound and preparation method and application thereof | 内蒙古大学 | 2023-05-23 | — | — | CN | disclosed |