Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 7/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | OXTR | P30559 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531225 | 0.92 | AVPR1A (0.53) | AVPR1AHRH3OXTROPRD1SIGMAR1 | |
| SCHEMBL1222056 | 0.87 | AVPR1A (0.59) | AVPR1AHRH3OXTRSIGMAR1AVPR2 | |
| SCHEMBL29990866 | 0.87 | AVPR1A (0.59) | AVPR1AHRH3OXTRSIGMAR1AVPR2 | |
| SCHEMBL6993813 | 0.87 | AVPR1A (0.59) | AVPR1AHRH3OXTRSIGMAR1AVPR2 | |
| SCHEMBL15963290 | 0.85 | AVPR1A (0.52) | AVPR1AHRH3OPRD1SIGMAR1 | |
| SCHEMBL4212516 | 0.85 | AVPR1A (0.55) | AVPR1AHRH3OXTRSIGMAR1AVPR2 | |
| SCHEMBL5368398 | 0.83 | HRH3 (0.61) | AVPR1AHRH3OXTRSIGMAR1AVPR2 | |
| SCHEMBL15963111 | 0.83 | AVPR1A (0.62) | AVPR1AHRH3OXTRAVPR2 | |
| SCHEMBL4220206 | 0.82 | AVPR1A (0.53) | AVPR1AHRH3OXTRAVPR2 | |
| SCHEMBL4211401 | 0.82 | HRH3 (0.55) | AVPR1AHRH3OXTRAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085212-B | Isoindoline compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-05-02 | — | — | CN | disclosed |