Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133755 | 0.97 | TSHR (0.44) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Water SCHEMBL31053126 | 0.94 | TSHR (0.41) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Bromide SCHEMBL11016656 | 0.94 | TSHR (0.41) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Ammonia Solution, Strong SCHEMBL27880779 | 0.94 | TSHR (0.41) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Bromide SCHEMBL970342 | 0.94 | TSHR (0.41) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Fluoride Ion SCHEMBL19812466 | 0.94 | TSHR (0.41) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Hydrochloric Acid SCHEMBL78546 | 0.94 | KDM4E (0.47) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Water SCHEMBL28482257 | 0.94 | TSHR (0.41) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Iodide SCHEMBL3467912 | 0.94 | TSHR (0.41) | TSHRNFKB1KCNA1KDM4EPMP22 | |
| Iodide SCHEMBL27864420 | 0.91 | TSHR (0.39) | TSHRNFKB1KCNA1KDM4EPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789897-A | Cement-based self-repairing material and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-09-22 | — | — | CN | claimed |
| CN-116462810-A | Fluid loss additive, preparation method thereof, drilling fluid containing fluid loss additive and application of drilling fluid | 中国石油大学(北京) | 2023-07-21 | — | — | CN | claimed |
| CN-116371460-A | Preparation method of zeolite molecular sieve encapsulated metal catalyst for methane dry reforming | 杭州极弱磁场重大科技基础设施研究院 | 2023-07-04 | — | — | CN | claimed |
| CN-107257777-B | High solids PCC with cationic additive | OMYA国际股份公司 | 2019-12-17 | — | — | CN | claimed |
| CN-106391097-B | Porous ZSM-5 zeolite and γ-Al2O3The synthesis of composite material and prepare Hydrobon catalyst | 常州大学 | 2019-10-11 | — | — | CN | claimed |
| US-20180016439-A1 | HIGH SOLIDS PCC WITH CATIONIC ADDITIVE | OMYA INTERNATIONAL AG (CH) | 2018-01-18 | — | — | US | claimed |
| EP-3261992-A1 | HIGH SOLIDS PCC WITH CATIONIC ADDITIVE | Omya International AG (CH) | 2018-01-03 | — | — | EP | claimed |
| EP-3061729-B1 | High solids PCC with cationic additive | OMYA INT AG (CH) | 2017-12-27 | — | — | EP | claimed |
| WO-2016135059-A1 | HIGH SOLIDS PCC WITH CATIONIC ADDITIVE | OMYA INTERNATIONAL AG (CH) | 2016-09-01 | — | — | WO | claimed |
| EP-3061729-A1 | High solids PCC with cationic additive | Omya International AG (CH) | 2016-08-31 | — | — | EP | claimed |
| US-5611934-A | REDUCTION, NEUTRALIZATION, FLOCCULATION | HOECHST CELANESE CORPORATION (US) | 1997-03-18 | — | — | US | claimed |
| EP-0628658-A1 | Cellulosic, modified lignin and cationic polymer composition and process for making improved paper or paperboard | CALGON CORPORATION (US) | 1994-12-14 | — | — | EP | claimed |
| US-5330656-A | Anionic polymer, cationic polyamine | CALGON CORPORATION (US) | 1994-07-19 | — | — | US | claimed |
| EP-0341357-B1 | Flocculation of suspended solids from aqueous solutions | CALGON CORP (US) | 1993-11-10 | — | — | EP | claimed |
| US-5035808-A | Synergistic mixture of ferric salt and cationic polymer such as a polyamine or diallyldialkylammonium halide; low turbidity waters | CALGON CORPORATION (US) | 1991-07-30 | — | — | US | claimed |
| EP-0366843-A1 | Flocculation of suspended solids from aqueous solutions | CALGON CORPORATION (US) | 1990-05-09 | — | — | EP | claimed |
| EP-0341357-A1 | Flocculation of suspended solids from aqueous solutions | CALGON CORPORATION (US) | 1989-11-15 | — | — | EP | claimed |
| US-4800039-A | SYNERGISTIC ALUMINUM CHLOROHYDRATE AND WATERSOLUBLE POLYAMINE OR CATIONIC ALLYL POLYMER | CALGON CORPORATION (US) | 1989-01-24 | — | — | US | claimed |
| US-4746457-A | SYNERGISTIC MIXTURE OF ALUMINUM CHLORIDE AND CATIONIC POLYMER | CALGON CORPORATION (US) | 1988-05-24 | — | — | US | claimed |
| US-3998602-A | ETCHING, GRAFT POLYMERIZATION IN SILVER SALT, CURING, ELECTROLESS DEPOSITION | HOROWITZ CARL | 1976-12-21 | — | — | US | claimed |