Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133755 | 0.97 | TSHR (0.44) | KDM4EPMP22ATMTSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL27863684 | 0.94 | KDM4E (0.42) | KDM4EPMP22ATMTSHRNFKB1 | |
| Bromide SCHEMBL303901 | 0.94 | TSHR (0.41) | KDM4EPMP22ATMTSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL1311617 | 0.94 | KDM4E (0.47) | KDM4EPMP22ATMTSHRNFKB1 | |
| Fluoride Ion SCHEMBL19812466 | 0.94 | TSHR (0.41) | KDM4EPMP22ATMTSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL23277158 | 0.94 | KDM4E (0.47) | KDM4EPMP22ATMTSHRNFKB1 | |
| Iodide SCHEMBL3467912 | 0.94 | TSHR (0.41) | KDM4EPMP22ATMTSHRNFKB1 | |
| Water SCHEMBL31053126 | 0.94 | TSHR (0.41) | KDM4EPMP22ATMTSHRNFKB1 | |
| Water SCHEMBL28482257 | 0.94 | TSHR (0.41) | KDM4EPMP22ATMTSHRNFKB1 | |
| Ammonia Solution, Strong SCHEMBL27880779 | 0.94 | TSHR (0.41) | KDM4EPMP22ATMTSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3372 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070397-A | Use of fast reverse cationic emulsion polymers with polyvinylamines as retention and drainage aids | 凯米拉公司 | 2026-05-19 | — | — | CN | claimed |
| EP-4739418-A2 | ONE-PASS DEOXYGENATION METHOD FOR POLYACRYLAMIDE PRODUCTION | KEMIRA OYJ (FI) | 2026-05-13 | — | — | EP | claimed |
| EP-4728136-A1 | STRENGTH SYNERGY BETWEEN POLYMER AND PAPERMAKING STRENGTH AID | Ecolab USA, Inc. (US) | 2026-04-22 | — | — | EP | claimed |
| US-12600867-B2 | Method of coating article, use for coating article, and polymerizable composition | GC CORPORATION (JP) | 2026-04-14 | — | — | US | claimed |
| EP-4716777-A2 | USE OF AMPHOTERIC EMULSION POLYMERS WITH STRENGTH RESINS AS RETENTION AND DRAINAGE AIDS | KEMIRA OYJ (FI) | 2026-04-01 | — | — | EP | claimed |
| US-12553188-B2 | GPAM compositions and methods | KEMIRA OYJ (FI) | 2026-02-17 | — | — | US | claimed |
| EP-4683950-A1 | DUAL EMULSIFICATION OF ALKENYL SUCCINIC ANHYDRIDE TO IMPROVE SIZING PERFORMANCE AND STABILITY | KEMIRA OYJ (FI) | 2026-01-28 | — | — | EP | claimed |
| US-20250223225-A1 | CONSTRUCTION MATERIAL DRY MIXES CONTAINING SOLID VINYL ESTER RESINS | WACKER CHEMIE AG (DE) | 2025-07-10 | — | — | US | claimed |
| US-20250215649-A1 | HIGH MOLECULAR WEIGHT GPAM WITH ANIONIC POLYSACCHARIDE PROMOTER | KEMIRA OYJ (FI) | 2025-07-03 | — | — | US | claimed |
| CN-115516031-B | GPAM compositions and methods | 凯米拉公司 | 2025-06-17 | — | — | CN | claimed |
| US-4510059-A | REDUCING THE FORMATION OF SILICA DEPOSITS | CALGON CORPORATION (US) | 1985-04-09 | — | — | US | claimed |
| US-4489180-A | ANIONIC AND CATIONIC COPOLYMERS | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-12-18 | — | — | US | claimed |
| US-4484631-A | POLYMER OF QUATERNARY ALLYLAMMONIUM CHLORIDE, UNSATURATED SULFO AMIDE OR UNSATURATED ACID, THIRD MONOMER | CALGON CORPORATION (US) | 1984-11-27 | — | — | US | claimed |
| US-4460477-A | Use of a carboxylic functional polyampholyte to inhibit the precipitation and deposit of scale in aqueous systems | CALGON CORPORATION (US) | 1984-07-17 | — | — | US | claimed |
| US-4455240-A | CATIONIC POLYMERS | CALGON CORPORATION (US) | 1984-06-19 | — | — | US | claimed |
| US-4305860-A | Stable, pumpable, solvent-free colloidal polyampholyte latices, their preparation and use in paper | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1981-12-15 | — | — | US | claimed |
| US-4120815-A | Polymeric demulsifiers | CALGON CORPORATION (US) | 1978-10-17 | — | — | US | claimed |
| US-4077930-A | Self-inverting emulsions of dialkyldiallyl ammonium chloride polymers and copolymers | CALGON CORPORATION (US) | 1978-03-07 | — | — | US | claimed |
| US-4027008-A | Hair bleaching composition containing water-soluble amino and quaternary ammonium polymers | THE GILLETTE COMPANY (US) | 1977-05-31 | — | — | US | claimed |
| US-3986825-A | HAIR COLORING COMPOSITION CONTAINING WATER-SOLUBLE AMINO AND QUATERNARY AMMONIUM POLYMERS | THE GILLETTE COMPANY (US) | 1976-10-19 | — | — | US | claimed |