Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30391045 | 1.00 | KRAS (0.47) | KRAS | |
| SCHEMBL30391087 | 1.00 | KRAS (0.47) | KRAS | |
| Hydrochloric Acid SCHEMBL30391165 | 0.99 | KRAS (0.46) | KRAS | |
| SCHEMBL29936938 | 0.87 | KRAS (0.47) | KRAS | |
| SCHEMBL29680448 | 0.85 | KRAS (0.39) | KRAS | |
| SCHEMBL30887740 | 0.85 | KRAS (0.45) | KRAS | |
| SCHEMBL29418819 | 0.84 | KRAS (0.48) | KRAS | |
| SCHEMBL30704160 | 0.84 | KRAS (0.48) | KRAS | |
| SCHEMBL31194908 | 0.82 | KRAS (0.47) | KRAS | |
| SCHEMBL29679980 | 0.81 | KRAS (0.47) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182313-A1 | KRAS G12D INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |