SCHEMBL303922

SCHEMBL303922

[CH]=COC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid Methyl Ester SCHEMBL28219435 0.60
SCHEMBL28214776 0.60
SCHEMBL1472 0.59
SCHEMBL11205436 0.59
SCHEMBL346613 0.59
SCHEMBL346612 0.59
SCHEMBL57907 0.59
Formic Acid Methyl Ester SCHEMBL4133942 0.56
SCHEMBL119353 0.56
SCHEMBL1264015 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348384-A1 Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides UCB PHARMA GMBH (DE) 2023-11-02 US claimed
WO-2023087632-A1 ANTI-INFLAMMATORY ANALGESIC COMPOUND AND USE THEREOF 江苏新元素医药科技有限公司 2023-05-25 WO claimed
US-11345662-B2 Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides UCB PHARMA GMBH (DE) 2022-05-31 US claimed
US-20220048858-A1 Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides UCB PHARMA GMBH (DE) 2022-02-17 US claimed
US-8710084-B2 Tetrazolyl oxime derivative, salt thereof, and plant disease control agent NIPPON SODA CO., LTD. (JP) 2014-04-29 US claimed
US-20110092491-A1 Compounds and Compositions as Inhibitors of Receptor Tyrosine Kinase Activity NOVARTIS AG (CH) 2011-04-21 US claimed
US-20100056494-A1 PURINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS FOR THE TREATMENT OF PLASMODIUM RELATED DISEASES IRM LLC (BM) 2010-03-04 US claimed
US-7652047-B2 Phenylamino isothiazole carboxamidines as MEK inhibitors ARDEA BIOSCIENCES, INC. (US) 2010-01-26 US claimed
EP-2124954-A2 PURINE COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS FOR THE TREATMENT OF PLASMODIUM RELATED DISEASES IRM LLC (BM) 2009-12-02 EP claimed
US-20080306063-A1 PHENYLAMINO ISOTHIAZOLE CARBOXAMIDINES AS MEK INHIBITORS ARDEA BIOSCIENCES, INC. (US) 2008-12-11 US claimed
WO-2006133417-A1 PHENYLAMINO ISOTHIAZOLE CARBOXAMIDINES AS MEK INHIBITORS VALEANT PHARMACEUTICALS INTERNATIONAL (US) 2006-12-14 WO claimed
US-20060194802-A1 Phenylamino isothiazole carboxamidines as MEK inhibitors ARDEA BIOSCIENCES, INC. 2006-08-31 US claimed
WO-2006091905-A1 BICYCLO (3.1.0) HEXANE DERIVATIVES AS ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2006-08-31 WO claimed
EP-1546163-B1 METHOD FOR THE PRODUCTION OF ACYLPHOSPHINE OXIDES BASF AG (DE) 2006-07-12 EP claimed
EP-1656378-A2 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF RECEPTOR TYROSINE KINASE ACTIVITY IRM LLC (BM) 2006-05-17 EP claimed
US-20060052636-A1 Method for the production of acylphosphine oxides BASF AKTIENGESELLSCHAFT (DE) 2006-03-09 US claimed
EP-1546163-A1 METHOD FOR THE PRODUCTION OF ACYLPHOSPHINE OXIDES BASF AKTIENGESELLSCHAFT (DE) 2005-06-29 EP claimed
US-20050124637-A1 Compounds and compositions as inhibitors of receptor tyrosine kinase activity IRM LLC (BM) 2005-06-09 US claimed
WO-2005016528-A2 6-SUBSTITUTED ANILINO PURINES AS RTK INHIBITORS IRM LLC (BM) 2005-02-24 WO claimed
WO-2004029063-A1 METHOD FOR THE PRODUCTION OF ACYLPHOSPHINE OXIDES BASF AKTIENGESELLSCHAFT (DE) 2004-04-08 WO claimed