Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.46 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.41 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.41 |
| ▸ | EPHA5 | P54756 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099028 | 1.00 | EGFR (0.50) | EGFRERBB2MAPK7GAKRIPK2 | |
| SCHEMBL26103141 | 0.96 | EGFR (0.49) | EGFRERBB2MAPK7KITPDE10A | |
| SCHEMBL26103317 | 0.92 | EGFR (0.48) | EGFRERBB2MAPK7KITPDE10A | |
| SCHEMBL30891778 | 0.90 | MAPK7 (0.45) | EGFRERBB2MAPK7GAKRIPK2 | |
| SCHEMBL26099862 | 0.90 | MAPK7 (0.45) | EGFRERBB2MAPK7GAKRIPK2 | |
| SCHEMBL26103463 | 0.88 | MAPK7 (0.44) | EGFRERBB2MAPK7EPHA2EPHB4 | |
| SCHEMBL26100926 | 0.88 | EGFR (0.47) | EGFRERBB2MAPK7KIT | |
| SCHEMBL26102740 | 0.86 | EGFR (0.45) | EGFRERBB2MAPK7EPHA2EPHB4 | |
| SCHEMBL26101576 | 0.86 | EGFR (0.45) | EGFRERBB2MAPK7KITPDE10A | |
| SCHEMBL26135306 | 0.86 | EGFR (0.45) | EGFRERBB2MAPK7KITPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | disclosed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |